Brain cancer can occur for one of many reasons but how exactly does this condition progress, one on the outside has to wonder? Well, most of it has to do with the presence of enzymes and how they are able to trigger the condition to become more severe with time. This is the case for glioblastoma, in particular, which is regarded as the most aggressive form of the cancer in question. Can a new method come into effect, though, for the sake of halting a particular enzyme?
Futurity posted an article that went into detail about a method that could come into play. It was described as a "backdoor" approach that would be followed through with in order to help brain cancer. The ability to halt an enzyme related to glioblastoma is one that deserves to be considered, as organizations such as Voices against Brain Cancer would be able to tell you. The details on the matter may not be made clear, though, so what exactly do these include, one has to wonder?
The enzyme that was focused on was referred to as phospholipase D, though it's not just in the realm of brain cancer that this has been seen. Other types of cancers like breast and gastric have been correlated to it as well, so it goes without saying that it has seen a great deal of attention in the way of science. PLD is also responsible for the regulation of Akt, another enzyme that is integral to cancer growth. There are many more details than I would have expected to uncover before reading this report.
PLD was given a tremendous amount of focus during a study with mice, each of the subjects afflicted with glioblastoma. One would assume that simply locking Akt would aid the problem but, as the article detailed, it is a course of action that stands a great chance of creating strong actions in the body. An exaggerated immune response, for example, could come to the surface. This subject deserves focus, without question, but care is another element that shouldn't be ignored.
Professor Craig Lindsley spoke about the concept of the isoform related to Akt being targeted without bringing any kind of harm to the patient. Keep in mind that if Akt is not activated, the cancerous cells in the body die out, which is especially worthy of note when considering that the patient is not harmed as a result. Safety should be top priority when talking about any field of research. The focus given on certain enzymes, in my opinion, is one that can open up greater possibilities.
Futurity posted an article that went into detail about a method that could come into play. It was described as a "backdoor" approach that would be followed through with in order to help brain cancer. The ability to halt an enzyme related to glioblastoma is one that deserves to be considered, as organizations such as Voices against Brain Cancer would be able to tell you. The details on the matter may not be made clear, though, so what exactly do these include, one has to wonder?
The enzyme that was focused on was referred to as phospholipase D, though it's not just in the realm of brain cancer that this has been seen. Other types of cancers like breast and gastric have been correlated to it as well, so it goes without saying that it has seen a great deal of attention in the way of science. PLD is also responsible for the regulation of Akt, another enzyme that is integral to cancer growth. There are many more details than I would have expected to uncover before reading this report.
PLD was given a tremendous amount of focus during a study with mice, each of the subjects afflicted with glioblastoma. One would assume that simply locking Akt would aid the problem but, as the article detailed, it is a course of action that stands a great chance of creating strong actions in the body. An exaggerated immune response, for example, could come to the surface. This subject deserves focus, without question, but care is another element that shouldn't be ignored.
Professor Craig Lindsley spoke about the concept of the isoform related to Akt being targeted without bringing any kind of harm to the patient. Keep in mind that if Akt is not activated, the cancerous cells in the body die out, which is especially worthy of note when considering that the patient is not harmed as a result. Safety should be top priority when talking about any field of research. The focus given on certain enzymes, in my opinion, is one that can open up greater possibilities.
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If you'd like to learn more about feats to raise awareness for brain cancer, please visit Voices against Brain Cancer.
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